PARP1/2 的抑制作用强于其母体化合物 Olaparib (HY-10162)。在同源重组修复 (HR) 缺陷细胞中,Simmiparib 诱导 DNA 双链断裂 (DSB) 积累和 G2/M 阻滞,从而诱导细胞凋亡 (apoptosis
YCH1899MedChemExpress (MCE)美国YCH1899是一种具有口服活性的PARP抑制剂,对PARP1/2的IC50均小于0.001 nM。YCH1899对Olaparib (HY-10162) 耐药和
or olaparib-induced DNA replication stress.存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year关键字: Mcl-1 inhibitor 223 | MI
ovarian cancer PDX model. Venadaparib also dose-dependently inhibits potent tumor growth compared to the Olaparib
activity, PARP1-IN-9 surpasses Olaparib in terms of efficacy [1].体外活性: PARP1-IN-9 (Compound 5c) shows antiproliferative
when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib .存储条件: Powder: -20°C
inhibition compared to Olaparib treatment group[1].存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year关键字
effect of the PARP inhibitor olaparib.存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year关键字: MFH-290 | OAT1441 | MFH290 | OAT-1441 | MFH 290
| Valproic Acid | Olaparib | Resveratrol | Doxazosin mesylate | Brefeldin A相关库: Anti-Aging Compound Library
|N-Descyclopropanecarbaldehyde Olaparib|4-[4-Fluoro-3-(piperazine-1-carbonyl)benzyl]phthalazi纯度:97%货号:F590117Cas号:763111-47-3
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