-
selectivity over a wide panel of kinases, as well as excellent selectivity versus unrelated receptor enzymes and ion
-
nM。体外活性: KU-0060648 exhibits differential effects on growth inhibition, but is not profoundly cytotoxic in a panel
-
值为2.3 nM。体外活性: CCT-251921 demonstrates minimal activity when tested in a panel of 55 receptors, ion channels
-
体外活性: GNE-272 does not inhibit any target at >30% when tested at 10 μM in 35 kinase panel and 42 receptors off-target
-
activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic,and GABA receptors, except
-
a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 0.085-0.26 and 3.4-16
-
is highly selective (>1,000-fold) for SETD7, over a panel of 18 other human protein methyltransferases and DNMT1
-
to human foreskin fibroblasts (HFFs). Cipargamin shows effective activities against a panel of culture-adapted P.
-
, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell
-
most abundant circulating protein albumin/ALB.; (Microbial infection) Acts as an uncoating receptor for a panel of echoviruses including Echovirus 5, 6, 7, 9, 11, 13, 25 and 29.