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(PDK2, PDK4, PDK1, and PDK3 with IC50 of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM , respectively).体内活性: PS10, inhibits all
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of tetrazoles Reagent used in Preparation of · PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis
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: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile描述: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 是一种 PDK1
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活性成分,具有很强的抗肿瘤活性。它是 JNK 信号通路的激活剂,也是 PDK1/Akt/mTOR 信号传导的抑制剂。它诱导自噬,G2/M 期阻滞和细胞凋亡。存储条件: Powder: -20°C for 3 years
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: 醌氧化还原酶 1 和PDK1的抑制剂,它们的IC50值分别为 0.37 和 19.42 μM。存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year溶解度: DMSO
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, AYPGKF and SFLLRN. TBCA also inhibits phosphorylation of PDK1, Akt, and GSK3β induced by AYPGKF[2].存储条件: Powder: -20°C
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, respectively. TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family
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平滑肌细胞和上皮细胞。BTC 对 ErbB1/EGFR 和 ErbB4 具有高亲和力和特异性,可诱导某些上皮细胞类型的生长。配体-受体结合后形成的同源或异源 ErbB 家族受体二聚体,激活 PI3K/PDK1/Akt、RAS/RAF/MEK
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the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1
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Antibody (YA1569)Synonyms: PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1基因 ID:5170品牌介绍:• MCE