Emricasan (IDN 6556; PF 03491390) is a member of a new class of drugs to modulate caspases (cell death
inhibitors modulate MDR in resistant cancer cells.
is a bioactive metabolite of DEHP which inhibits the 17,20 lyase activity of CYP17. MEHP has been shown to modulate
Kynurenic acid synthesis which demonstrates the ability to modulate neuronal degeneration. L-α-Aminoadipic acid is a inhibitor
conditions. In addition, Delta agonists are thought to modulate other biological processes that may manifest themselves
been demonstrated to modulate cell proliferation depending on the concentration of TRAM-34. Mechanistic studies have
and antiprotozoal agents. It has been shown to modulate amyloid beta-peptide accumulation via upregulation of metalloprotease activity.
) inhibitor with anti-proliferative properties. This compound has been shown to modulate purified bovine pituitary 20 S
α,25-Dihydroxyvitamin D3 has widespread effects on cellular differentiation and proliferation, and can modulate immune
in brain membranes). Shown to block anandamide breakdown in rat cortical neurons (IC50 = 500 pM) and modulate anxiety
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