A hedgehog [Hh] signaling pathway and Smo inhibitor.
Hedgehog (Hh) 抑制剂,在哺乳动物细胞中,IC50 为 30 nM
应用 A potent hedgehog (Hh) signaling
,Erismodegib)是一种Smoothened(Smo)拮抗剂,抑制Hedgehog (Hh)信号通路,IC50分别为1.3 nM (小鼠)和2.5 nM(人
An activator of the hedgehog (Hh) signaling pathway.
of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway. Antitumor agent.
· Inhibitors of Gli1-mediated transcription in the Hedgehog pathway · Serotonin 5-HT6 antagonists · Very Late Antigen-4
inhibitor . Potential antivascular agents . Gli1-mediated transcription in the Hedgehog pathway . Inhibitors of receptor
of Gli1-mediated transcription in the Hedgehog pathway · Potent DNA-topoisomerase II poisons and anti-MDR agents · Protein kinase
transcription in Hedgehog pathway ? Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue
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