blocked mTORC2-dependent phosphorylation of AKT in vitro and in vivo. In various cancer cells, WYE-687 inhibited the mTORC1
In various cancer cells, WAY-600 inhibited the mTORC1 substrate P-S6K(T389) and mTORC2 substrate P-AKT(S473) at submicromolar
of mTORC1 signaling and stimulates autophagy in vitro. Niclosamide displays antineoplastic effects in acute myelogenous
to be a an ATP-competitive mTORC1/mTORC2 (FRAP) inhibitor (IC50 = 8 nM). PP242 is the first selective inhibitor that targets
the phosphorylation of mTORC1 (p70S6K and 4E-BP1) as well as phosphorylation of the mTORC2 (Akt) and downstream proteins.
。Dihydromyricetin 可通过抑制 mTOR 信号从而激活自噬。Dihydromyricetin 抑制 mTOR 复合体 (mTORC1/2) 形成
mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells;Immunity 47, 538–551,DOI:10.1016
The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells;Immunity 47, 538–551,DOI
in Bovine Mammary Epithelial Cells;Journal of Cellular Physiology,DOI 10.1002/jcp.26255The Kinase mTORC1 Promotes
质谱盛会西安开幕:汇聚全球智慧 共绘质谱新章
沃特世国产液质联用系统首发,持续加码本土化布局
美国将37个中国实体列入“黑名单” 含一所高校 多家科研院所
沃特世大刀阔斧谱新章 多款高端液质全面中国造
安益谱“发射”Cassitrap 让每家实验室都能拥有超高分辨质谱
2024年1-4月离子色谱中标盘点,龙头品牌占半壁江山
第八届华人质谱研讨会 展现科研新趋势
重磅!骆初平出任月旭科技总经理
总投资539.82亿元 贵州发布第一批大规模设备更新清单
国办印发《关于创新完善体制机制 推动招标投标市场规范健康发展的意见》
咨询热线: 010-84839035
联系邮箱: sales@antpedia.net